Osteochondral repair using an acellular dermal matrix-pilot in vivo study in a rabbit osteochondral defect model
نویسندگان
چکیده
منابع مشابه
Using Xenogenic (Calf Foetal) Osteochondral Transplantation for Articular Cartilage Defect in Rabbit Model
Background: The destruction of articular cartilage is the major cause of articular problems. The articular cartilage has little repair postertial due to lack of perichondrium and direct blood circulation. It is, therefore important to consider this phenomena in surgical treatments. One of the articular cartilage reconstructive surgeries is using Osteo-Chondral graft. The main purpose of this re...
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Cell-based therapies are currently being used in treating osteochondral defect (OCD), but technical advances are needed to tackle the problems of scaffold and grafting technique. This study aimed to test the potential of allogeneic scaffold-free bioengineered chondrocyte pellet (BCP) in treating OCD. BCP was fabricated from rabbit costal cartilage and implanted into 3 mm × 3 mm OCD in medial fe...
متن کاملBiomimetic biphasic scaffolds for osteochondral defect repair
The osteochondral defects caused by vigorous trauma or physical disease are difficult to be managed. Tissue engineering provides a possible option to regenerate the damaged osteochondral tissues. For osteochondral reconstruction, one intact scaffold should be considered to support the regeneration of both cartilage and subchondral bone. Therefore, the biphasic scaffolds with the mimic structure...
متن کاملAugmentation of osteochondral repair with hyperbaric oxygenation: a rabbit study
BACKGROUND Current treatments for osteochondral injuries often result in suboptimal healing. We hypothesized that the combination of hyperbaric oxygen (HBO) and fibrin would be superior to either method alone in treating full-thickness osteochondral defects. METHODS Osteochondral repair was evaluated in 4 treatment groups (control, fibrin, HBO, and HBO+fibrin groups) at 2-12 weeks after surgi...
متن کاملContaminated osteochondral plugs: effect of different sterilizing solutions: an experimental study in the rabbit
Background: To determine the efficacy of different antiseptic solutions (Control group (I), Antibiotic solution (II), Chlorhexidine 0.4% (III), and povidone – iodine 10% (IV)) in sterilizing contaminated osteochondral plugs. Methods: Under sterile conditions, the femoral head and condyles of 20 rabbits were removed and cut into equal osteochondral pieces. A total of 200 osteochondral specimens...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research®
سال: 2018
ISSN: 0736-0266
DOI: 10.1002/jor.23837